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News Release
For immediate release
Eye Health Potential
Shown in New GliSODin® Supplement Study.
Benefits for AMD?
MORRISTOWN, NJ --- (15 Nov 2006)
PL Thomas (PLT) and its partner Isocell (Paris, France) today
announced the results of a new study using the exclusive dietary
supplement ingredient, GliSODin®, demonstrating significant
protection against induced oxidative stress and retinal tissues
in an animal model. In this study, GliSODin supplementation
limited retinal oxidative stress and improved plasma antioxidant
status.
Oxidative stress from reactive oxygen species has been
implicated in many health issues and may play an important role
in Age-related Macular Degeneration by negatively targeting the
pigment cell layer that nourishes the retinal cells.
Presented at the Association for Research in Vision and
Ophthalmology (ARVO) Eye Research Conference and now available
online at Investigational Ophthalmology and Vision Sciences,
researchers at the Eye and Nutrition Research Group, National
Institute for Research on Agronomy (Dijon, France) evaluated the
protective effect of the dietary supplement GliSODin.
http://abstracts.iovs.org/cgi/content/abstract/47/5/2089.This
research was independent and the researchers have no affiliation
with PLT or Isocell.
The researchers induced oxidative stress in a recognized model
using light exposure to the eyes once each month for three
months. Prior to the third exposure, GliSODin (10.8mg/kg) or
placebo were administered for seven days. Retinal response,
levels of induced oxidants in eye tissues and blood anti-oxidant
levels were measured.
In this study, light exposure did not demonstrate a significant
difference between the active and control groups as measured by
retinal degeneration. However, blood antioxidant capacity was
increased by 30% in the GliSODin group. Further, cell oxidant
levels, measured by the potent oxidant superoxide anion, were
increased by up to 50% in retinal cell layer and by 300% in the
outer nuclear layer in all light exposed animals compared to
control (P<.01). GliSODin supplementation decreased the
superoxide anion levels significantly (P<.05).
The researchers concluded that light-exposure promotes retinal
oxidative stress while GliSODin supplementation efficiently
limits retinal oxidative stress by increasing plasma antioxidant
capacity.
Previous published human and laboratory studies have shown
GliSODin’s effectiveness in protecting cells from oxidative
stress by activating the body’s production of its own
antioxidants, including SOD, catalase and glutathione peroxidase.*
More information is available at the research site
www.glisodin.org.
This “internal antioxidant defense system” is necessary for the
elimination of the free radicals produced by oxidative stress,
resulting in tangible health benefits, including helping protect
cellular DNA from oxidative stress, inhibit photo-oxidative
stress in the sun-sensitive, inhibit lactic acid accumulation
under exercise, help restore normal levels of SOD, and
positively affect other significant markers of oxidative stress.
About GliSODin
GliSODin® is patented and trademarked by Isocell, Paris, France.
It is available in North America as a nutritional raw material
exclusively from PL Thomas & Co., Morristown, NJ. Numerous in
vivo and human studies support the use of GliSODin in
nutritional applications
About PLT
P.L. Thomas & Co., Inc., a New Jersey-based ingredient supplier,
offers fifty years of innovation in securing reliable, high
quality raw materials for the food/functional food and nutrition
industries.
For more information, please contact
PL Thomas: phone: 973-984-0900, fax: 973-984-5666, e-mail: plt@plthomas.com
or www.plthomas.com.
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